For intravenous administration, what is the bioavailability F?

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Study for the Pharmaceutics Drug Disposition Test. Prepare with flashcards and multiple choice questions, each answer has hints and explanations. Get set for your exam!

Multiple Choice

For intravenous administration, what is the bioavailability F?

Explanation:
Bioavailability F is the fraction of an administered dose that reaches systemic circulation. For intravenous administration, the drug is delivered directly into the bloodstream, bypassing absorption barriers and first-pass metabolism, so the entire dose becomes available systemically. Therefore, F equals 1 (or 100%). The other values would imply no delivery, partial delivery, or more drug in circulation than was given, which isn’t possible with IV administration.

Bioavailability F is the fraction of an administered dose that reaches systemic circulation. For intravenous administration, the drug is delivered directly into the bloodstream, bypassing absorption barriers and first-pass metabolism, so the entire dose becomes available systemically. Therefore, F equals 1 (or 100%). The other values would imply no delivery, partial delivery, or more drug in circulation than was given, which isn’t possible with IV administration.

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